Inflammation, Recovery, Skeletal Muscle Hypertrophy
07/18/1422:47
Doug and said:
“I am not sure what to make of the study from the article about it. With 36 subjects total, it is unlikely to have enough statistical power to reach any conclusions. Their conclusion seems counter-intuitive to me. I will try to get the full text article to review.
Doug McGuff”
Doug,
I read the full text of the study when it was first published some time ago, although I can’t seem to find it at the moment (I have 3000+ studies on my hard drive). Strictly from my recollection, I was skeptical of the results immediately. Not only was it contradictory to almost all of the previously published data, but the delta between the control group and treatments groups were huge (60% greater CSA increase in the treatment groups). I’m not sure we would see such a difference with anabolic steroids and untrained subjects over that short of a time period. Read More...
“I am not sure what to make of the study from the article about it. With 36 subjects total, it is unlikely to have enough statistical power to reach any conclusions. Their conclusion seems counter-intuitive to me. I will try to get the full text article to review.
Doug McGuff”
Doug,
I read the full text of the study when it was first published some time ago, although I can’t seem to find it at the moment (I have 3000+ studies on my hard drive). Strictly from my recollection, I was skeptical of the results immediately. Not only was it contradictory to almost all of the previously published data, but the delta between the control group and treatments groups were huge (60% greater CSA increase in the treatment groups). I’m not sure we would see such a difference with anabolic steroids and untrained subjects over that short of a time period. Read More...
Comments
Age as a Factor in Recovery from Exercise
07/18/1422:17
Joe,
“How age-dependent is this? Given the huge difference in other areas of healing depending on how old you are, it seems that muscle healing would vary similarly. I could imagine that a healthy 18 year old would be able to repair much more muscle in far less time than a healthy 50 year old. This might lead to the discrepancies in different studies on recovery time (between 2 days and more than 14 days).”
Yes, age does make difference in the requisite time to recover from exercise induced microtrauma (although, I think most of the variability is more related to genotype). In animal models, older rats showed a reduced up-regulated expression of IGF-1 splice variants when compared to younger animals. However, expression was still increased almost 3-fold over untrained conditions.
See the following: Read More...
“How age-dependent is this? Given the huge difference in other areas of healing depending on how old you are, it seems that muscle healing would vary similarly. I could imagine that a healthy 18 year old would be able to repair much more muscle in far less time than a healthy 50 year old. This might lead to the discrepancies in different studies on recovery time (between 2 days and more than 14 days).”
Yes, age does make difference in the requisite time to recover from exercise induced microtrauma (although, I think most of the variability is more related to genotype). In animal models, older rats showed a reduced up-regulated expression of IGF-1 splice variants when compared to younger animals. However, expression was still increased almost 3-fold over untrained conditions.
See the following: Read More...
